Psychiatric Genetics and Genomics

Portada
Peter McGuffin, Michael J Owen, Irving I Gottesman
OUP Oxford, 2004 M09 23 - 492 páginas
From reviews of the hardback:'It is timely to see such an excellent textbook... Aimed at graduate level students, this book is complex enough to be thorough, but clear with enough background to be accessible... the coverage is comprehensive and the flow logical... The text is uniformly well written and achieves a successful integration.' -The Lancet'A good introduction and reference book for professionals interested in psychiatric genetics such as psychiatrists, clinical psychologists and neuroscientists... the book you want to have on your bookshelf to look up material and obtain a complete and balanced picture of the field.' -Psychological MedicineRevised for paperback edition, with new appendicesGenetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations.The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future.The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.Readership: Psychiatrists, clinical psychologists, geneticists, neuroscientists and neurologists
 

Contenido

Basic molecular genetics
3
Quantitative genetics
31
Linkage and association
55
The genetics of normal and abnormal development
75
Personality and cognitive abilities
77
Genetics of mental retardation
113
Reading and language disorders
129
Childhood disorders
147
Substance misuse
267
Anxiety and eating disorders
303
The dementias
341
Applications and implications
395
Psychopharmacogenetics
397
Genetic counselling
419
Ethical considerations in psychiatric genetics
429
The future and postgenomic psychiatry
449

The genetics of abnormal behaviour in adult life
181
Personality disorders
183
Genetics of affective disorders
211
Schizophrenia
247
A brief guide to internet addresses for psychiatric genetics and genomics
465
Psychiatric genetics and genomics an update
469
Index
485
Derechos de autor

Otras ediciones - Ver todas

Términos y frases comunes

Acerca del autor (2004)

Irving Isadore Gottesman was born in Cleveland, Ohio on December 29, 1930. He served in the Naval Reserve Officers Training Corps and was a communications officer for three years during the Korean War. He received a bachelor's degree in psychology from the Illinois Institute of Technology in 1953 and a doctorate in psychology from the University of Minnesota. He taught at several universities during his lifetime including Harvard University, Washington University in St. Louis, the University of Virginia, and the University of Minnesota. His work on the role of heredity in schizophrenia helped transform the way people thought about the origins of mental illness. In the 1960s, he conducted a study of schizophrenia in British twins with James Shields. The study, which found that identical twins were more likely than fraternal twins to share a diagnosis of schizophrenia, provided strong evidence for a genetic component to the illness and challenged the prevailing view at the time that it was caused by bad mothering. The findings also emphasized the contribution of a patient's environment. He also studied several other aspects of human behavior, from autism and alcoholism to violence and post-traumatic stress disorder in Vietnam veterans. He wrote 17 books and more than 300 papers. He died on June 29, 2016 at the age of 85.

Información bibliográfica