Medical Therapy of Breast CancerZenon Rayter, Janine Mansi Cambridge University Press, 2003 M01 9 - 394 páginas There have been very significant advances across many areas of the study, investigation and treatment of breast cancer. This publication surveys how scientific advances have influenced, improved and extended therapeutic options. The volume spans prevention, screening, genetics, and treatment of pre-invasive breast cancer, before focusing in depth on management of established breast cancer. This includes chapters on the various therapeutic options available and their role in treating breast cancer from the very earliest stage through to advanced and metastatic breast cancer. In addition, the text looks forward at the potential for emerging experimental strategies to become adopted into medical management in the future. The volume concludes with a chapter on palliative care. This wide-ranging account will be essential for breast cancer specialists, trainees in oncology and clinical research scientists. |
Contenido
| 1 | |
2 Chemoprevention of breast cancer | 37 |
3 Familial breast cancer | 61 |
4 Hormone replacement therapy and breast cancer | 72 |
5 Screening for breast cancer | 103 |
6 The management of in situ breast cancer | 126 |
7 Adjuvant systemic therapy | 153 |
8 Adjuvant radiotherapy in the management of breast cancer | 178 |
9 Predictors of response and resistance to medical therapy | 209 |
10 Primary medical therapy in breast cancer | 264 |
11 Medical therapy of advanced disease | 283 |
12 Experimental approaches | 309 |
13 The place of bisphosphonates in the management of breast cancer | 340 |
14 Palliative care in breast cancer | 357 |
| 386 | |
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5-fluorouracil adjuvant chemotherapy adjuvant tamoxifen adjuvant therapy advanced breast cancer apoptosis associated benefit biopsy bisphosphonates bone metastases BRCA1 breast cancer breast cancer cells breast cancer patients breast carcinoma breast-conserving surgery British Journal Clinical Oncology clinical trials clodronate compared conservative surgery cyclophosphamide cytotoxic DCIS detected docetaxel dose doxorubicin drug early breast cancer effect endocrine therapy England Journal epirubicin ER-positive European Journal evaluation excision Fisher follow-up gene growth factor high-dose chemotherapy hormone human breast cancer hypercalcaemia increased inhibitors invasive irradiation Journal of Cancer Journal of Clinical Journal of Medicine Lancet lesions mammography margin Medical menopausal metastatic metastatic breast cancer mutations National Cancer Institute node-negative node-positive oestrogen ovarian overall survival paclitaxel pain placebo postmenopausal postmenopausal women Powles primary breast cancer prognostic protein radiation radiotherapy raloxifene randomised randomized trial recurrence reduced regimens replacement therapy reported response rate Society of Clinical steroid surgical tamoxifen tissue treatment tumour Veronesi