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" Botstein D, Risch N. Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease. "
Genética Médica - Página 276
por Lynn B. Jorde - 2004 - 376 páginas
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Principles of Sex-based Differences in Physiology

Virginia L. Miller, Virginia M. Miller, Meredith Hay - 2004 - 356 páginas
...relationship to bone mass variation in postmenopausal Italian women. Hum. Mol. Genet. 9, 2043-2050. [3] Botstein, D., Risch, N., 2003. Discovering genotypes...future approaches for complex disease. Nat. Genet. 33(Suppl.), 228-237. [4] Cardon, LR, Abecasis, GR, 2003. Using haplotype blocks to map human complex...
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Nutrigenetics and Nutrigenomics

Artemis P. Simopoulos, J. M. Ordovas - 2004 - 337 páginas
...1995. 43 Popper KR: A World of Propensities. Bristol, Thoemmes Press, 1995. 44 Botstein D, Risch N: Discovering genotypes underlying human phenotypes:...disease, future approaches for complex disease. Nat Genet 2003;33:228-237. 45 Morowitz H: Phenetics, a born again science. Complexity 2003;8:12-13. 46 Smith...
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Genetics of Autoimmunity

Gregory R. Bock, Jamie A. Goode - 2005 - 264 páginas
...Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31. Gut 52:1133-1139 Botstein D, Risch N 2003 Discovering genotypes underlying...approaches for complex disease. Nat Genet 33:228237 Daly MJ, Rioux JD, Schaffner SF, Hudson T|, Lander ES 2001 High-resolution haplotype Frazer KA, Wade...
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Drug Discovery Handbook

Shayne Cox Gad - 2005 - 1494 páginas
...E., Kumm, J., Ronaghi, M. (2004). Global genetic analysis. /. Biochem. Mol. Biol., 37(1), 11-27. 58. Botstein, D., Risch, N. (2003). Discovering genotypes...future approaches for complex disease. Nat. Genet., 33 (Suppl.), 228-237. 59. Patil, N., Berno, AJ, Hinds, DA, Barrett, WA, Doshi, JM, Hacker, CR, Kautzer,...
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An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases

Jack J. Pasternak - 2005 - 656 páginas
...Missense/nonsense Regulatory Repeat sequences Splicing Frequency (%) 1.8 21.8 6.8 58.9 0.8 0.1 9.8 From Botstein D, Risch N (2003). Discovering genotypes...disease, future approaches for complex disease. Nat Genet 33 Suppl:228— 237. Nomenclature for Mutations Because of the availability of complete sequences of...
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Mammalian Genomics

Anatoly Ruvinsky, Jennifer A. Marshall Graves - 2005 - 614 páginas
...Boehnke, M. (2000) A look at linkage disequilibrium. Nature Genetics 25, 246-247. Botstein, D. and Risch, N. (2003) Discovering genotypes underlying...mendelian disease, future approaches for complex disease. Nature Genetics 33 (Suppl.), 228-237. Bovenhuis, H. and Meuwissen, T. (1996) Course Detection and Mapping...
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Clinical Genetics in Nursing Practice: Third Edition

Felissa R. Lashley - 2005 - 590 páginas
...297-305. Bell, J. (2004). Predicting disease using genomics. Nature, 429, 453-456. Botstein, D., & Risch, N. (2003). Discovering genotypes underlying...Mendelian disease, future approaches for complex disease. Nature Genetics Supplement, 33, 228-237. Cardon, LR, & Bell, JI (2001 ). Association study designs...
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Molecular Mechanisms of Cardiac Hypertrophy and Failure

Richard A. Walsh - 2005 - 812 páginas
...residual confounding and the resiliency of race. Epidemiology 1997; 8: 621-8. Botstein D, Risch N. Discovering genotypes underlying human phenotypes:...disease, future approaches for complex disease. Nat Genet 2003; 33 (Suppl):228-37. Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev...
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Psychopathology in the Genome and Neuroscience Era

Charles F. Zorumski, Eugene H. Rubin, American Psychopathological Association - 2007 - 256 páginas
...with inherited vulnerability to schizophrenia. Biol Psychiatry 47:245-251, 2000 Botstein D, Risch N: Discovering genotypes underlying human phenotypes:...disease, future approaches for complex disease. Nat Genet 33(suppl):228-237, 2003 Brant SR, Fu Y, Fields CT, et al: American families with Crohn's disease have...
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Prevention of Occurrence and Recurrence of Human Hepatocarcinogenesis

Soo Ryang Kim, O. Hino, Masatoshi Kudo - 2005 - 76 páginas
...Searching for genetic determinants in the new millennium. Nature 2000;405:847856. 7 Botstein D, Risch N: Discovering genotypes underlying human phenotypes:...disease, future approaches for complex disease. Nat Genet 2003;33(suppl): 228-237. 8 Kruglyak L, Nickerson DA: Variation is the spice of life. Nat Genet 2001;27:234-236....
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