Psychiatric Genetics and GenomicsPeter McGuffin, Michael J Owen, Irving I Gottesman OUP Oxford, 2004 M09 23 - 492 páginas Revised for paperback edition, with new appendices Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations. The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors. |
Contenido
Basic molecular genetics | 3 |
Quantitative genetics | 31 |
Linkage and association | 55 |
The genetics of normal and abnormal development | 75 |
Personality and cognitive abilities | 77 |
Genetics of mental retardation | 113 |
Reading and language disorders | 129 |
Childhood disorders | 147 |
Substance misuse | 267 |
Anxiety and eating disorders | 303 |
The dementias | 341 |
Applications and implications | 395 |
Psychopharmacogenetics | 397 |
Genetic counselling | 419 |
Ethical considerations in psychiatric genetics | 429 |
The future and postgenomic psychiatry | 449 |
The genetics of abnormal behaviour in adult life | 181 |
Personality disorders | 183 |
Genetics of affective disorders | 211 |
Schizophrenia | 247 |
A brief guide to internet addresses for psychiatric genetics and genomics | 465 |
Psychiatric genetics and genomics an update | 469 |
485 | |
Otras ediciones - Ver todas
Psychiatric Genetics and Genomics Peter McGuffin,Michael J. Owen,Irving I. Gottesman Sin vista previa disponible - 2002 |
Términos y frases comunes
abnormalities abuse ADHD adolescents adoption studies affective disorder Agoraphobia alcohol dependence allele Alzheimer's disease antisocial behaviour anxiety disorders APOE Apolipoprotein Archives association studies autism bipolar disorder candidate genes cent chromosome clinical clozapine cognitive abilities comorbidity concordance correlation dementia diagnosis dopamine drug DSM-III environment evidence family studies female genetic and environmental genetic influence genetic research genetic studies genome genotype heritability Hum Genet human Huntington's disease identified increased individuals interaction Journal of Psychiatry Kendler K. S. loci locus lod score major depression male markers McGuffin mental retardation mice molecular genetic mutations neuronal non-shared onset parents personality disorder phenotype phobia Plomin polymorphism population prevalence probands protein psychiatric disorders psychiatric genetics Psychiatry quantitative rates receptor gene region replication reported risk factors sample schizophrenia sequence serotonin transporter siblings specific suggest susceptibility symptoms syndrome traits transmission twin pairs twin study unipolar variance variation