Psychiatric Genetics and Genomics

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Peter McGuffin, Michael J Owen, Irving I Gottesman
OUP Oxford, Sep 23, 2004 - 492 páginas
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Revised for paperback edition, with new appendices Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations. The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.
 

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Contenido

Basic molecular genetics
3
Quantitative genetics
31
Linkage and association
55
The genetics of normal and abnormal development
75
Personality and cognitive abilities
77
Genetics of mental retardation
113
Reading and language disorders
129
Childhood disorders
147
Substance misuse
267
Anxiety and eating disorders
303
The dementias
341
Applications and implications
395
Psychopharmacogenetics
397
Genetic counselling
419
Ethical considerations in psychiatric genetics
429
The future and postgenomic psychiatry
449

The genetics of abnormal behaviour in adult life
181
Personality disorders
183
Genetics of affective disorders
211
Schizophrenia
247
A brief guide to internet addresses for psychiatric genetics and genomics
465
Psychiatric genetics and genomics an update
469
Index
485
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Acerca del autor (2004)

Peter McGuffin is at SGDP Centre, Institute of Psychiatry, Denmark Hill, London, UK. Michael J Owen is in the Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK. Irving Gottesman is at the University of Minnesota.

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