Biostatistical Genetics and Genetic EpidemiologyRobert C. Elston, Jane M. Olson, Lyle Palmer John Wiley & Sons, 2002 M04 22 - 800 páginas Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference. |
Contenido
Conclusions | 21 |
Accurate estimates of age of onset are crucial to clini | 141 |
Bayes Theorem | 379 |
10 Hopper J L Southey M C Dite G S Jolley D J | 423 |
75 | 685 |
Otras ediciones - Ver todas
Biostatistical Genetics and Genetic Epidemiology Robert C. Elston,Jane M. Olson,Lyle Palmer Vista previa limitada - 2002 |
Biostatistical Genetics and Genetic Epidemiology Robert C. Elston,Jane M. Olson,Lyle Palmer Vista de fragmentos - 2002 |
Biostatistical Genetics and Genetic Epidemiology Robert C. Elston,Jane M. Olson,Lyle Palmer Sin vista previa disponible - 2002 |
Términos y frases comunes
algorithm allele frequencies American Journal Annals applications approach approximation ascertainment assumed assumption asymptotic bias biological Biometrics Biometrika bootstrap case-cohort case-control studies cell chromosome coefficient cohort study complex components compute conditional confounding controls correlation covariates defined denote detect disease effects error esti example exposure factors function gene Genetic Epidemiology genome genotype Gibbs sampling given haplotype Human Genetics individuals inference inheritance interaction interval Journal of Human likelihood ratio linear model linkage analysis linkage disequilibrium loci locus lod score logistic regression mapping marginal marker Markov chain matching mating matrix measure methods Molecular Monte Carlo multiple multivariate mutation normal distribution null hypothesis observed odds ratio pairs parameters parents pedigree phenotype polymorphisms population probability problem procedure quantitative trait random recombination fraction regression model Research residuals sample segregation analysis sequence sibship specific tion variables variance vector